Synthesis, structure, magnetic properties and dna cleavage of binuclear cuii schiffbase complexes yingying kou, a jinlei tian, a dongdong li, a wen gu, a xin liu. Synthesis, demetallation, remetallation and transmetallation. Molecular structures, spectral and sar study ahmed m. The binucleating schiff bases are then allowed to react with the ethanol solution of copperii acetate.
Synthesis and characterisation of some novel schiff base. The low molar conductance of the complexes in dimethylsulfoxide shows their non. Lbinucleating n2o2 schiff bases prepared by condensing 4,4diaminobiphenyl with salicylaldehyde. Preparation of novel binuclear manganeseiii complexes with. The template synthesis, spectral characterization and thermal. Issn 2348 7968 synthesis, spectroscopic and antimicrobial. Binuclear metal complexes that contain schiff base ligands are useful to study the relation between structures and. Synthesis and spectroscopic studies of new binuclear transition.
Pdf binuclear tetrahedral dimeric mgii complexes of. Synthesis, structure, magnetic properties and dna cleavage of binuclear cuii schiffbase complexes yingying kou, a jinlei tian, a dongdong li, a wen gu, a xin liu, a shiping yan, a daizheng liao a and peng cheng a. The spectral and esr data suggest distortion of environment around coppertlf complexes towards. A potentially active schiff base ligand and their binuclear copper complexes have been prepared by the condensation of 2,6diformyl4methyl phenol and 2aminobenzoic acid in the molar ratio 1. Binuclear schiff base ligand and its metalii complexes. The basal plane is formed by the o,n,odonor set of the tridentate schiff base ligand and a phenoxo bridging oxygen, while a pyridine or a dmf molecule is located at the apex of the pyramid. Synthesis, structural characterization, antimicrobial. The template synthesis, spectral characterization and thermal behaviour of new binuclear schiff base complexes derived from naminopyrimidine with 2,3butandion mehmet sonmeza and memet ekercib adepartment of chemistry, faculty of science and arts, yuzuncu yil, university, 65080, van.
The syntheses and characterization of a series of binuclear cobalt complexes of the octadentate schiffbase calixpyrrole ligand l are described. The cobaltii complex co 2 l was prepared by a transamination method and was found to adopt a wedged, pac. The resultant binuclear complex thus has one of the metal ions in diaquo form. Binuclear manganese ii complexes of a new schiff base as. In the past couple of decades, the properties of schiff base metal complexes have stimulated huge interest for their note worthy contributions to material science8, catalysis of many reactions9 and their industrial applications10. Synthesis, structure, magnetic properties and dna cleavage of.
Pdf monoand binuclear schiff base complexes derived from. Synthesis, spectral characterization, electrochemical, antimicrobial. Pdf some mgii complexes of dibasic tridentate schiff base ligands derived from aldehydes and orthoaminophenol have been synthesized. Synthesis, spectroscopic and biological studies of some new. Schiff base complex, thermal analysis, antimicrobial activity, conductivity measurements.
Introduction the reactions of aldehyde or ketone with primarily amine in which carbonyl group is replaced by imine group is called schiff bases, are widely used in organic synthesis 1. Pdf a new series of mixed complexes were synthesized have 1. A hydroxybenzohydrazidebased schiff base ligand was conveniently synthesized. Schiffbase ligands that are able to form binuclear transition metal complexes are useful to study the relation between structures and magnetic exchange. The schiff base ligand can coordinate with two copper ions to form binuclear complexes after the deprotonation of the. The conjugations through the bridge provide flexibility of the monomer in the electropolymerization stage. Binuclear and polynuclear complexes of schiff bases. Preparation and properties of dinuclear schiff base complexes.
The syntheses of binuclear schiff base metal complexes are increasing, due to their applications in the area such as catalysis, enzymatic reaction, magnetism and. The data on the synthesis of binuclear and polynuclear homo and heterometallic complexes of aromatic and heterocyclic azole schiff bases are summarized and systematized. Schiff base complexes are used in many fields such as pharmaceutical industry, biological activity, agriculture and organic synthesis 2, 3. New mono and binuclear copperii complexes with schiff bases derived. Synthesis of the schiff base ligand schiff base ligands was synthesized as follows. New binuclear coii and coii complexes of ono tridentate heterocyclic schiff base derived from 4aminoantipyrine with salicylaldehyde have been synthesized and characterized on the bases of elemental analysis, uvvis. Prabakarakrishnan and 3kannappan geetha pg and research department of chemistry, muthurangam govt. Binuclear cobaltii, nickelii, copperii and palladiumii complexes. The resulting complexes are coloured solids with sharp melting points and these are soluble in benzene, chloroform, dmf and dmso. Synthesis characterisation of binuclear siliconaluminium.
The in vitro biological activity of the schiff base ligand and the binuclear complexes was assessed against bacteria staphylococcus aureusbacillus. The binuclear schiff base complexes of arsenic and aluminium were found to be insoluble in most of the organic solvents. Mixed complexes, binuclear, 1,10phenanthroline,antibacterial activities. Chapteriv schiff base compartmental binuclear ruthenium iii. Preparation, characterization and study of the photodecolorization of mixedligand binuclear coii complex of schiff base by zno. Synthesis and characterization of binuclear cuii complexes. Analytical data of the schiff base ligands and its binuclear metal complexes infrared spectra the comparative ir spectra of the ligands and cuii complexes gave elaborate details about the. The schiff base ligand l1 is the bidentate n,n chelating donor of pyrpzamide. Synthesis, spectral characterization, invitro antioxidant. Schiff base ligand from the condensation of 2, 6diamino pyridine with benzil and the complexation with metal ions to form potentially active macrocyclic binuclear schiff base metal complexes. Pdf binuclear tetrahedral dimeric mgii complexes of dibasic. Read preparation of novel binuclear manganeseiii complexes with schiff base ligands and their reactivities toward hydrogen peroxide, journal of inorganic biochemistry on deepdyve, the largest online rental service for scholarly research with thousands of academic publications available at your fingertips. Biological activity, spectroscopic and dna cleavage of.
Introduction hugo schiff was the first scientist who described schiff bases in 1864. A new series of binuclear rutheniumiii schiff base complexes of the type b2x2ru2l where, b pph3 or asph3. Pdf preparation, characterization and study of the. Binuclear cobalt complexes of schiffbase calixpyrroles and. Abstractthe binuclear ruii complexes with schiff bases derived from 5chlorosalicyladehyde and 2aminopyridine and its 5substituted salicylideneimine homologues were tested in vitro against cervical carcinoma hela, metastatic colorectal adenocarcinoma sw620, lung adenocarcinoma a549, breast adenocarcinoma mcf7, and human lung fibroblast wi38 cell lines. Pdf applications of 2aminophenol derived schiff base. Introduction schiff bases with powerful donor atoms such as imine nitrogen and carboxylate oxygen are extraordinary in catalysis, structural richness and wide range of biological. Bydirect interaction of the schiff base with the metal salts the schiff base can be synthesized without using the metal ion and then followed by addition of the metal ion as salt solution for complex formation. The ligands and their metal complexes have been characterized by elemental analyses, conductivity and magnetic susceptibility measurements, i. Selective coordination ability of sulfamethazine schiffbase ligand towards copperii.
The syntheses and characterization of a series of binuclear cobalt complexes of the octadentate schiff base calixpyrrole ligand l are described. Schiff base ligands have significant importance in chemistry, especially in the development of schiff base complexes, because schiff base complexes are potentially capable of forming stable complexes with metal ions, many schiff base complexes show excellent catalytic. Chemistry department, faculty of science, cairo university, gamaa street, giza 126, egypt highlights new mono and binuclear cuii complexes of a sulfamethazine schiffbase were prepared. The macrocyclic binuclear schiff base metal complexes were characterized by elemental analysis, molar conductivity, ir, uv, epr and electrochemical studies are gives satisfactory results. Synthesis, spectral, thermal analyses and molecular modeling of. Cyclopalladated binuclear complexes of schiff bases. Microwave preparation and spectroscopic investigation of. The binuclear schiff base complexes were found to be higher antibacterial activity than the free ligand.
All the synthesized complexes were characterized based on. The complexes are nonelectrolytes in dmf and dmso and are monomeric in nature. Synthesis and mesogenic properties of binuclear copper ii. Homo and hetero binuclear schiff base complexes of feii,znii and mnii were prepared by intercomplex reaction between the corresponding metal complexes of 3ethoxy salicylaldehyde and 2amino 3hydroxy pyridine. Electropolymerization using binuclear nickelii schiff base. Oct 07, 2014 a hydroxybenzohydrazidebased schiff base ligand was conveniently synthesized. Binuclear copperii coba1tii complexes of tetradentate. Schiff base metal complexes have occupied a central place in the development of coordination chemistry after the work of jorgensen and werner 28.
The cobaltii complex co 2 l was prepared by a transamination method and was found to adopt a wedged, pacman geometry in the solid state and in solution. In view of above application of schiff base complexes we report the synthesis of a series of binuclear. Binuclear cobalt complexes of schiffbase calixpyrroles. Schiff bases importance increased due to a wide range of appli. A series of homo and hetero binuclear schiff base metal complexes, derived from mononuclear schiff base complex which behaves as a ligand using transition metal ions such as cuii, and niii with the title ligand has been prepared. Synthesis, spectroscopic and antimicrobial studies of binuclear. The literature survey showed that the chelating schiff base ligands derived from 2aminophenol compounds encompass a highly remarkable class of compounds having a wide range of applications in clinical, biochemical and physiological activities. The supramolecular building blocks from a nickelii bisalphentype complex have been reported. The complexes of mn ii and ni ii with schiff base derived from salicylaldehyde and 2amino benzoic acid have been prepared and characterized by gravimetry, potentiometry, molar conductance and. Preparation and properties of dinuclear schiff base. Synthesis, spectroscopic characterization, and biological screening.
The ligands and their metal complexes have been characterized by elemental analyses, conductivity and magnetic susceptibility. Mixed1,10phenanthroline with mnii, cuii,coii, hgii. In vitro anticancer activity of binuclear ruii complexes. The complexes have been characterized in the light of elemental analyses, spectral ir, uvvis. Br analogues of the binuclear complexes behave similarly but with. The room temperature effective magnetic moment of these complexes as a solid is 1. Synthesis, characterization, and crystal structure of new binuclear. The invitro antimicrobial activities of the synthesized compounds have been tested against the gram negative and gram positive bacterias.
A cyclic voltammetric study of niii complex shows a couple of oneelectron anodic responses near 0. Dna binding interaction studies of binuclear schiff base cu. The elemental analyses of the complexes confine to octahedral geometry for binuclear cuii complexes. Pdf monoand binuclear schiff base complexes derived. Vancheesan department of chemistry, indian institute. Structural elucidation of newly synthesized potentially. Schiff base ligands have significant importance in chemistry, especially in the development of schiff base complexes, because schiff base complexes are potentially capable of forming stable complexes with metal ions, many schiff base complexes show excellent catalytic activity in various reaction at high temperature and. The activity data show the metal complexes to be more potent antibacterials than the parent schi.
The imine nitrogen of the schiff base was allowed to coordinate with the metal nearby while the deficiency created at the metal ion on aldehyde end was sufficed by aquo ligands liberated during imine formation. The copperji complexes, iv, vii, x and xiii, are paramagnetic in the solid state and in solution. Binuclear schiff base complexes derived from glycine gly and 3acetylpyridine 3apy in the presence of m oac 2 m co ii, ni ii, cu ii, zn ii and cd ii have been synthesized. The schiff base and its complexes have been characterized by elemental analysis. Analytical data of the schiff base ligands and its binuclear metal complexes infrared spectra the comparative ir spectra of the ligands and cuii complexes gave elaborate details about the binding behavior of the ligand with metal ions. Two new binucleating ligands, pentylbis3bae and octylbis3bae and their copperii and nickelii complexes have been prepared and characte. Binuclear copperfl l and cobaltii complexes of new tetradentate schiff base ligands derived from the condensation of some diamines with salicylaldehydel or pentane2,4dioneio have been synthesised and investigated by magnetic and spectral methods. The cobaltii complex co2l was prepared by a transamination method and was found to adopt a wedged, pac. The chemistry of transition metal complexes with schiff base ligands is attracting increasing attention by chemists and has undergone a spectac ular growth. Synthesis and spectroscopic studies of new binuclear transition metal complexes of schiff bases derived from 4,6diacetylresorcinol. Impact of heterogenization on liquid phase catalytic oxidation of a series of alkenes abhishek maurya department of chemistry, indian institute of technology indian school of mines, dhanbad, 826004 jharkhand, india. Synthesis and mesogenic properties of binuclear copperii complexes derived from salicylaldimine schiff bases. The binuclear complexes were employed as catalysts in the rop of raclactide for polylactide pla synthesis.
Microwave preparation and spectroscopic investigation of binuclear schiff base metal complexes derived from 2,6diaminopyridine with salicylaldehyde. Schiff base, binuclear metal, complexes, 2,6diaminopyridine, salicylaldehyde 1. Antimicrobial activity studies of the binuclear metal. Synthesis and characterization of bioactive binuclear. The role of ph in promoting the condensation of glycine and. This can be easily described by the following example. Binuclear manganese ii complexes of a new schiff base. Schiff base compartmental binuclear ruthenium iii complexes the condensation products of primary amine with carbonyl compounds was first reported by h.
Experimental physical measurements apparatus and experimental conditions. Schiff1 in 1864 and the products are schiff bases and are also known as anils, imines or azomethines. Pdf characterization of binuclear schiff base researchgate. A new symmetrical schiff base ligand was derived from 1,6diaminohexane and 2,2dihydroxy salicylalacetone and then it is allowed to react with metal salts to form binuclear schiff base metal complexes.
Schiff base metal complexes have been known since the mid nineteenth century 27 and even before the general preparation of the schiff base ligands themselves. Synthesis, characterisation and antimicrobial activity of. Complex 1 crystallizes in the triclinic crystal system with space group p1. Influence is revealed of the structure nature of aldehyde and amine moieties and intermetallic bridges of azomethine binuclear copper chelates on their magnetic characteristics. Three novel tridentate schiff base ligands derived from. Synthesis, characterisation and antimicrobial activity of binuclear manganeseii complexes containing pentadentate schiff base ligand 1n. The cobaltii complex co2l was prepared by a transamination method and was found to adopt a wedged, pacman geometry in the solid state and in solution. The schiff base structure affords a greater choice and flexibility, and complexation with a metal ion adds. The dna cleaving capacity of all the complexes was analyzed by agarose gel electrophoresis. The complexes were characterized by elemental analysis and estimation of metals.
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